Regulating heart beat

Regulating heart beat

In the 1930s, the ability of the local anesthetic procaine to regulate the heart beat (also called anti-arrhythmic activity) is discovered. This type of pharmaceutical treatment is complex and can be quite difficult because drugs that block arrhythmia can cause arrhythmia under certain conditions.


Procaine was the first of many drugs that were eventually approved for this use, including procainamide, lidocaine, and flecamide (drugs made similar to procaine that regulate heart rate) and beta-blockers and sodium channel antagonists (drugs originally created to lower blood pressure).

Did you know?

The average human heart, beating one hundred thousand times a day, will beat approximately 2.5 billion times during an average 66-year lifespan! The blood pumped out by the heart circulates throughout the blood vessels of a human body in approx. 25 seconds. The length of these blood vessels is around 100,000 km, which means it could run around the Equator two times!