The first compressor-assisted refrigerator made for home use was introduced in 1918
Since being introduced for home use in 1918, refrigeration has altered food preservation by providing the ability to transport and store fresh foods safely. In the early 1920s refrigerators were unpopular since the sulfur-dioxide coolant proved to be toxic.
The solution was Freon 12, a chlorofluorocarbon (also referred to as a CFC, CCl2F2) compound made into a refrigerant gas by Thomas Midgley and Charles Kettering in 1931. Refrigerators quickly became standard in homes, restaurants, and grocery stores.
Freon's role is now being discontinued because of its role in the destruction of the earth's ozone layer. Concerns with the depletion of the ozone layer have led to increased use of isobutane as a gas for refrigeration systems, especially in domestic refrigerators and freezers.