After her husband's death, the scientific world turned its eyes on Marie. In 1910, with her colleagues' assistance, she isolated the pure radium metal. A year later, she received a Nobel Prize in Chemistry, in recognition of the discovery of the elements radium and polonium, and the isolation of radium and the study of the nature and compounds of this element. This made Marie the first scientist to receive two Nobel Prizes.
The second Nobel Prize opened up even more professional opportunities to her. The greatest achievement was the building of the Radium Institute (now the Institut Curie) in Paris, which opened its gates in 1918 to support research in chemistry, physics, and medicine. Following this, Marie primarily focused on her research in the field of chemistry and the medical application of radioactive elements. She also founded the Radium Institute in Warsaw.
Nevertheless, she was never elected a member of the French Academy of Sciences because of its prejudice against women and hatred against foreigners.